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Sotorasib for previously treated KRAS G12C mutation-positive advanced non-small-cell lung cancer

Jul 9, 2026

BTOG wishes to inform members of a new NICE release that has been published today.   Following review of the original technical appraisal, NICE no longer recommend sotorasib for treating KRAS G12C mutation-positive locally advanced or metastatic non-small-cell...

Serplulimab with carboplatin and etoposide for untreated extensive-stage small-cell lung cancer

May 29, 2026

BTOG wishes to inform members of a new NICE release that has been published today.   NICE has recommended serplulimab with carboplatin and etoposide within its marketing authorisation, as an option for untreated extensive-stage small cell lung cancer in adults....

Cemiplimab with platinum-based chemotherapy for untreated advanced non-small-cell lung cancer

May 26, 2026

BTOG wishes to inform members of a new NICE release that has been published today.   NICE has recommended cemiplimab with platinum-based chemotherapy – it can be used as an option for untreated non-small-cell lung cancer (NSCLC) in adults: if they would...

Amivantamab with carboplatin and pemetrexed during the managed access period as an option for untreated advanced NSCLC with activating ex20ins mutations in adults

May 8, 2026

BTOG wishes to inform members of a new NICE release that has been published today.   NICE has recommended amivantamab with carboplatin and pemetrexed during the managed access period as an option for untreated advanced non-small-cell lung cancer (NSCLC) with...

Osimertinib for maintenance treatment of EGFR mutation-positive unresectable locally advanced non-small-cell lung cancer after platinum-based chemoradiotherapy

May 7, 2026

BTOG wishes to inform members of a new NICE release that has been published today.   NICE has recommended osimertinib, within its marketing authorisation, as an option to treat unresectable locally advanced (stage 3) non-small-cell lung cancer (NSCLC) in adults....

Encorafenib plus binimetinib as an option to treat BRAF V600E mutation-positive advanced NSCLC

Apr 21, 2026

BTOG wishes to inform members of a new NICE release that has been published today.   NICE has recommended encorafenib plus binimetinib as an option to treat BRAF V600E mutation-positive advanced non-small-cell lung cancer (NSCLC) in adults, only if it is used at...
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